Endotoxin & Sterility Testing
Acculize Incu-Bi Smart Biological Indicator Incubator
Standalone dry bath incubator for biological indicators, with temperature data logging at 37 °C and 60 °C.
The Acculize Incu-Bi Smart is a standalone dry bath incubator for biological indicator (BI) testing in pharma QC and sterility assurance.
It is part of the Acculize dry bath series alongside the Acculize BET 96 Plus and Acculize BET 96 Smart dry baths for the LAL test, with the same touchscreen control, dual-sensor safety and printed temperature data logging.
Key Features
- High-capacity well block with integrated vial crusher, 50+ BIs per run
- 5" colour touchscreen HMI with live temperature graph
- Dual PT1000 sensors; automatic heater cut-off above 150 °C
- Temperature data logging every 1 to 60 min, up to 14 days, printed on A4 or 3-inch dot-matrix printers
- Stability and uniformity ±1.0 °C at 37 °C, ±2.0 °C at 60 °C; resolution 0.1 °C
- Supports qualification per USP <1058> (Group B instrument)
Built for biological indicator testing
01
50+ BIs in one run
The high-capacity well block removes the incubation bottleneck for sterilisation cycle validation and routine monitoring.
02
Integrated vial crusher
Activate self-contained biological indicators at the instrument, consistently, before incubation.
03
37 °C and 60 °C incubation
Covers common BI organisms, for example G. stearothermophilus for steam and B. atrophaeus for EO and dry heat.
04
5" touchscreen HMI
Real-time temperature display, live temperature graph, setpoint and timer at a glance.
05
Temperature data logging
Continuous printed temperature records on A4 or 3-inch printers for paper-based documentation of every run.
06
Thermal safety
Dual Pt1000 sensors, independent safety monitoring and automatic heater cut-off above 150 °C.
Technical Specifications
| Application | Incubation of biological indicators (BIs) for sterilisation validation and monitoring |
|---|---|
| Capacity | 50+ biological indicator tubes per run |
| Vial crusher | Integrated, for activating self-contained BIs |
| Incubation temperatures | 37 °C and 60 °C |
| Temperature resolution | 0.1 °C |
| Temperature stability | ±1.0 °C at 37 °C; ±2.0 °C at 60 °C |
| Temperature uniformity | ±1.0 °C at 37 °C; ±2.0 °C at 60 °C |
| Display | 5" colour touchscreen HMI with real-time temperature and live temperature graph |
| Alerts | Buzzer alerts for pre-heat complete and sample timer complete |
| Warnings | On-screen pop-ups for clock low battery, sensor failure, over-temperature and low voltage |
| Printing | Compatible with A4 and 3-inch dot-matrix printers for continuous printing |
| Printed data | Maximum, minimum and average temperature, start and stop time, setpoints, timer settings, completion status |
| Logging interval | 1 to 60 minutes (configurable) |
| Logging duration | 1 minute to 14 days (configurable) |
| Temperature sensors | Dual Pt1000 with independent safety monitoring |
| Over-temperature protection | Automatic heater cut-off above 150 °C |
| Qualification | Supports instrument qualification per USP <1058> (Group B); IQ/OQ documentation available |
Frequently Asked Questions
The Acculize Incu-Bi Smart is a standalone dry bath incubator for biological indicator (BI) testing in pharma QC and sterility assurance. It incubates the BIs used to validate and monitor steam, dry heat, ethylene oxide and other sterilisation processes.
The high-capacity well block holds 50+ biological indicator tubes, so a full sterilisation load can be incubated in a single run.
The Acculize Incu-Bi Smart incubates at 37 °C and 60 °C, with ±1.0 °C stability and uniformity at 37 °C, ±2.0 °C at 60 °C, and 0.1 °C resolution. 55 to 60 °C is typical for Geobacillus stearothermophilus indicators (steam) and 30 to 37 °C for Bacillus atrophaeus indicators (EO and dry heat). Always follow the incubation conditions specified by your BI manufacturer.
The Acculize Incu-Bi Smart automates temperature control during incubation, temperature data logging and printing, and buzzer alerts when pre-heating and the sample timer complete. Analysts still activate the BIs with the vial crusher and read the results.
Self-contained biological indicators are activated by crushing the inner media ampoule after sterilisation. The integrated vial crusher lets analysts do this at the instrument, consistently, before placing the BI in the well block.
The Acculize Incu-Bi Smart connects to A4 and 3-inch dot-matrix printers for continuous printing. Printouts include maximum, minimum and average temperature, start and stop time, setpoints, timer settings and completion status, with logging intervals from 1 to 60 minutes and durations up to 14 days.
Yes. The Acculize Incu-Bi Smart is a Group B instrument under USP <1058> and supports instrument qualification, with IQ/OQ documentation available. Regulatory compliance depends on the user's validated system and procedures; Acculize lab devices provide the technical controls and documentation to support it.
The Acculize BET 96 Plus and Acculize BET 96 Smart are 96-well dry bath heating blocks for LAL gel clot bacterial endotoxin testing at 37 °C with 10x75 mm tubes. The Acculize Incu-Bi Smart is part of the same dry bath series, with a well block, vial crusher and 37 °C / 60 °C setpoints designed for biological indicators.
Yes. Acculize Innovations is based in Chennai, India. Contact us for a quote on this dry bath for biological indicators, for your lab in India or abroad.
Dual Pt1000 temperature sensors with independent safety monitoring, automatic heater cut-off above 150 °C, and on-screen warnings for sensor failure, over-temperature, low voltage and clock low battery.
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